Invented by Sadasivan VIDYASAGAR, Paul Okunieff, Lurong ZHANG, University of Florida Research Foundation Inc

The gastrointestinal system is a complex network of organs and tissues responsible for the digestion and absorption of nutrients from food. A healthy gastrointestinal function is crucial for overall health and wellbeing. However, many people suffer from gastrointestinal disorders such as irritable bowel syndrome, inflammatory bowel disease, and gastroesophageal reflux disease. The market for materials, methods, and materials for improving gastrointestinal function is growing rapidly as more people seek solutions to these conditions. One of the most popular materials for improving gastrointestinal function is probiotics. Probiotics are live bacteria and yeasts that are beneficial for the digestive system. They help to restore the natural balance of bacteria in the gut, which can be disrupted by factors such as antibiotics, stress, and poor diet. Probiotics are available in many forms, including capsules, powders, and fermented foods such as yogurt and kefir. Another material that is gaining popularity in the market is prebiotics. Prebiotics are non-digestible fibers that stimulate the growth of beneficial bacteria in the gut. They are found in foods such as onions, garlic, bananas, and asparagus. Prebiotics work in tandem with probiotics to improve gastrointestinal function and overall health. Methods for improving gastrointestinal function include dietary changes, exercise, and stress management. A healthy diet that is rich in fiber, fruits, and vegetables can promote regular bowel movements and prevent constipation. Exercise can also help to improve gastrointestinal function by increasing blood flow to the digestive system and promoting peristalsis, the wave-like contractions that move food through the digestive tract. Stress management techniques such as meditation and yoga can help to reduce stress and anxiety, which can contribute to gastrointestinal disorders. Materials for improving gastrointestinal function also include supplements such as digestive enzymes and fiber supplements. Digestive enzymes are enzymes that break down food into smaller molecules that can be absorbed by the body. They can be helpful for people who have difficulty digesting certain foods. Fiber supplements can help to promote regular bowel movements and prevent constipation. In conclusion, the market for materials, methods, and materials for improving gastrointestinal function is growing rapidly as more people seek solutions to gastrointestinal disorders. Probiotics, prebiotics, dietary changes, exercise, stress management, and supplements such as digestive enzymes and fiber supplements are all materials and methods that can help to improve gastrointestinal function and overall health. As research continues to uncover new ways to improve gastrointestinal function, the market for these materials and methods is likely to continue to grow.

The University of Florida Research Foundation Inc invention works as follows

The invention provides therapeutic compositions and uses thereof to treat or ameliorate injury to the small intestinal mucosa. Preferential embodiments include one or more nutrients or electrolytes with high absorption capacity.

Background for Materials, methods and materials for improving the gastrointestinal function

BRIEF DESCRIPTION DES DRAWINGS

DETAILED DISCLOSURE

Therapeutic Composition to Improve Small Intestine Function

Treatment Method to Improving Small Intestine Function.

Preparation and use of therapeutic compositions to improve small intestine function

Formulations and Administration.

Materials & Methods

Experimental Animals

Ion Flux Studies

Immunohistochemistry

Statistics

EXAMPLES

Example 1?” Radiation Increases Net Ion Secretion

Example 2?” Radiation Causes a Dose Dependent Increase in Short Circuit Currents (ISc).

Example 3:Decrease in Na+ or Cl? Absorption

Example 4: Radiation Causes Increased Paracellularpermeability

Example 5: Increase in Inflammatory Mediators due to Irradiation.

Example 6?” Decrease in Anion Secretion due to Irradiation are NKCC1 and CFTR-Dependent

Example 7: Decrease in HCO3? Secretion due to Irradiation

Example 8″: Irradiation Causes Lower Glucose Absorption

Example 9″ Irradiation Causes Reductions in Glutamine Transport

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